Erythema Nodosum Bumps

Erythema Nodosum (EN) is skin inflammation that involves bumps or nodules underneath the skin. The condition often presents along the shins or the front of the legs, below the knees. In some cases, nodules also appear on the calves, ankles, thighs and arms. Erythema nodosum inflammation first develops in the fatty layer of skin (the adipose tissue), and grows upward toward the skin's surface. The raised lumps are generally reddish in color and tender to the touch. They range from 1 to 5 centimeters in size. They may resolve spontaneously within 3-6 weeks, shrinking and flattening to leave a bruised appearance. Slight indentations where fatty layers beneath the surface have been compromised may also exist. Still, new lesions can appear in other areas and chronic (reoccurring) erythema nodosum can produce months of intermittent symptoms.

Nearly 50% of all cases have no specific cause, with the remainder of cases linked to a pre-existing health condition, infection or medication. Pre-existing conditions include streptococcal infections, tuberculosis, pneumonia, fungal infections, pregnancy, leukemia, Chron's disease and inflammatory bowel disease. Birth control pills and repeated antibiotic usage may also contribute to the condition. For unknown reasons, women are 4 times more likely to be affected by symptoms. Young adults are more susceptible than other age groups. Erythema Nodosum treatments vary depending on the severity and recurrence of the condition.

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