Inflammatory Skin Disease Caused by Missing Gatekeeper

February 1st, 2012 | General News

New research has provided a key understanding into why certain individuals’ skin become inflamed without a real reason.

Inflammation is your body’s natural immune response to injury or infection. It causes increased blood flow to transfer nutrients, white blood cells and heat to the affected area so that your body can properly heal and fight off any invading germs.

In some people, this reaction happens when it’s not supposed to. It’s irritating, can damage the skin further, cause infection and cause many other issues if the inflammation begins to run wild.

This research has found that an enzyme called ADAM17 could be the “gatekeeper” responsible for this immunal response. If this enzyme is deactivated in rats, the body will begin the “spontaneous production of inflammatory proteins by keratinocytes, culminating in skin inflammation and immune cell proliferation.”

This research will greatly advance treatments of skin infections in the future.

Learn how to avoid more damage to your skin, especially if it is Erythema Nodosum or Erysipelas.

Read more about this study on Medical News Today.


Aidance Skincare does not condone testing on animals and does not test any of it’s products on animals.

Leave a reply

Dr. Recommendations

Dr. Recommendations

Buy More, Get More!

Buy 2 Ship Free OR Buy 2 Get 1 Free

FREE Shipping!

Free Shipping

Looking for answers?

Aidance has you covered, from A-Z!

Visit our Skin Health FAQs section for more information on skin conditions, exclusive guides, and more. More Info